Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL

LigandBDBM50083773(2-(Biphenyl-4-sulfonylamino)-3-({5-[4-(pyridin-2-y...)Copy SMILESCopy InChI

Affinity DataIC50:  130nMAssay Description:Inhibition of vitronectin receptor (alpha V beta 3), expressed on human 293 cells, binding to immobilized fibrinogenMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL

LigandBDBM50083773(2-(Biphenyl-4-sulfonylamino)-3-({5-[4-(pyridin-2-y...)Copy SMILESCopy InChI

Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of platelet aggregation in human platelet rich plasma (PRP)More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI