Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Tyrosine-protein kinase JAK1 [866-1154]
(Homo sapiens (Human))
Hutchison Medipharma
US Patent
Ligand
BDBM228706
(US10369153, Compound 253 | US9346810, 253)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.0550nM
T: 2°C
Assay Description:
JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z'...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Hutchison Medipharma
US Patent
Ligand
BDBM228706
(US10369153, Compound 253 | US9346810, 253)
Copy SMILES
Copy InChI
Affinity Data
IC50: <100nM
Assay Description:
JAK1/2/3 kinase assay are performed in vitro using Kit-Tyr 6 Peptide (Invitrogen, Cat. No. PV4122). TYK2 kinase assay are performed in vitro using Z&...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI