Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Adolor

Curated by ChEMBL

LigandBDBM50205680(CHEMBL230711 | N1-((S)-2-((S)-3-hydroxypyrrolidin-...)Copy SMILESCopy InChI

Affinity DataKi:  280nMAssay Description:Agonist activity at human kappa opioid receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2D6(Homo sapiens (Human))
Adolor

Curated by ChEMBL

LigandBDBM50205680(CHEMBL230711 | N1-((S)-2-((S)-3-hydroxypyrrolidin-...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI