Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL

LigandBDBM50241096((S)-4-((6-(4'-fluoro-N-methylbiphenyl-4-ylcarboxam...)Copy SMILESCopy InChI

Affinity DataKi:  129nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL

LigandBDBM50241096((S)-4-((6-(4'-fluoro-N-methylbiphenyl-4-ylcarboxam...)Copy SMILESCopy InChI

Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL

LigandBDBM50241096((S)-4-((6-(4'-fluoro-N-methylbiphenyl-4-ylcarboxam...)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI