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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Isoform 1 of Metabotropic glutamate receptor 5 (5a)
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM234209
(US9359301, Reference compound 2)
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Affinity Data
Ki: 51nM
pH: 7.4
Assay Description:
For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Isoform 1 of Metabotropic glutamate receptor 5 (5a)
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM234209
(US9359301, Reference compound 2)
Copy SMILES
Copy InChI
Affinity Data
EC50: 23nM
T: 2°C
Assay Description:
A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Isoform 1 of Metabotropic glutamate receptor 5 (5a)
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM234209
(US9359301, Reference compound 2)
Copy SMILES
Copy InChI
Affinity Data
EC50: 51nM
pH: 7.4
Assay Description:
For binding experiments, cDNA encoding human mGlu 5a receptor was transiently transfected into EBNA cells using a procedure described by Schlaeger an...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI