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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50321582
(1-(3-aminopropyl)-8-(3-(2-(dimethylamino)-2-oxoeth...)
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Affinity Data
IC50: 85nM
Assay Description:
Inhibition of PDK1-mediated AKT1 phosphorylation at T308 in human H460 cells after 2 hrs by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50321582
(1-(3-aminopropyl)-8-(3-(2-(dimethylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 85nM
Assay Description:
Inhibition of PDK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Nerviano Medical Sciences
Curated by
ChEMBL
Ligand
BDBM50321582
(1-(3-aminopropyl)-8-(3-(2-(dimethylamino)-2-oxoeth...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 500nM
Assay Description:
Inhibition of CDK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI