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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Mitogen-activated protein kinase 8
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211438
(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
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Affinity Data
IC50: 15nM
Assay Description:
Inhibition of JNK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 9
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211438
(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 37nM
Assay Description:
Inhibition of JNK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Transcription factor Jun
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211438
(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
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Affinity Data
IC50: 741nM
Assay Description:
Inhibition of cJun translocation in IL1beta-stimulated A549 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Ucb Pharma
Curated by
ChEMBL
Ligand
BDBM50211438
(4-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.36E+3nM
Assay Description:
Inhibition of CDK2 by IMAP technology
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI