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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
60
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Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1.00E+3nM
Assay Description:
Tested for in vitro inhibition of acetylcholinesterase
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.30E+4nM
Assay Description:
Inhibition assay using AChE and BuChE.
More data for this Ligand-Target Pair
Target Info
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Target
Cholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.80E+4nM
Assay Description:
Inhibition assay using AChE and BuChE.
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.0430nM
Assay Description:
Inhibition of human acetylcholine esterase
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
Assay Description:
In vitro inhibitory activity against human recombinant AChE
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 18.8nM
Assay Description:
Inhibition of human whole RBC AChE pretreated for 30 mins by Ellman technique
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
Assay Description:
Inhibition of guinea pig acetylcholinesterase
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Rattus norvegicus (rat))
University Of Mysore
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 35nM
Assay Description:
Inhibition of Wistar rat brain AChE by Ellman colorimetric assay
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Rattus norvegicus (rat))
University Of Mysore
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 37.5nM
Assay Description:
Inhibition of rat brain homogenate AchE
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Rattus norvegicus (rat))
University Of Mysore
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibition of Wistar rat brain homogenate AChE by Ellman's assay
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 41nM
Assay Description:
Inhibition of human serum AChE by Ellman's assay
More data for this Ligand-Target Pair
Target Info
PDB
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Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 42.1nM
Assay Description:
Inhibition of human serum AchE
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 45nM
Assay Description:
Inhibition of human serum AChE by Ellman colorimetric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
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Ligand Info
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 47.5nM
Assay Description:
Inhibition of electric eel AChE by Ellman colorimetric assay
More data for this Ligand-Target Pair
Target Info
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 50nM
Assay Description:
Inhibition of electric eel AChE using acetylcholine iodide as substrate after 10 mins by Ellman method
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
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ChEBI
CHEMBL
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 50nM
pH: 8.0 T: 2°C
Assay Description:
Seven different concentrations of the synthesized compounds in the range 10^−3-10^−9 M were measured at 412 nm. All the assays were under...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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ChEBI
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 53nM
Assay Description:
Inhibition of electric eel AChE by Ellman's method
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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MCE
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PC sid
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PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 60nM
Assay Description:
Inhibition of human plasma BChE pretreated for 30 mins by Ellman technique
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
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Target
Cholinesterase
(Equus caballus (Horse))
University Of Life Sciences
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 70nM
Assay Description:
Inhibition of equine serum BChE using butylthiocholine iodide as substrate after 10 mins by Ellman method
More data for this Ligand-Target Pair
Target Info
PDB
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ChEBI
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Copy BDB DOI
Target
Acetylcholinesterase
(Rattus norvegicus (rat))
University Of Mysore
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 70nM
Assay Description:
Inhibition of AChE in rat brain Hippocampus
More data for this Ligand-Target Pair
Target Info
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Target
Carboxylic ester hydrolase
(Equus caballus (Horse))
University Of Life Sciences
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 70nM
pH: 8.0 T: 2°C
Assay Description:
Seven different concentrations of the synthesized compounds in the range 10^−3-10^−9 M were measured at 412 nm. All the assays were under...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
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Purchase
ChEBI
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 87nM
Assay Description:
In vitro inhibitory activity against acetylcholinesterase from electric eel
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
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ChEBI
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Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 91.0nM
Assay Description:
Inhibition acetylcholinesterase (AChE) enzyme.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 91nM
Assay Description:
Inhibitory activity against Acetylcholinesterase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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B.MOAD
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Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 100nM
pH: 7.4
Assay Description:
Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
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B.MOAD
DrugBank
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Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 100nM
Assay Description:
Inhibition of human erythrocyte AChE after 5 mins by Ellman's method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Ligand Info
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Target
Cholinesterase
(Equus caballus (Horse))
University Of Life Sciences
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 160nM
More data for this Ligand-Target Pair
Target Info
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 600nM
Assay Description:
In vitro inhibitory activity against acetylcholinesterase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
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KEGG
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Target
Acetylcholinesterase
(Rattus norvegicus (rat))
University Of Mysore
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 650nM
Assay Description:
Inhibition of AChE in rat brain cortex
More data for this Ligand-Target Pair
Target Info
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Target
Cholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 800nM
pH: 7.4
Assay Description:
Human erythrocyte AChE or human plasmatic BChE (Prague, Aldrich; commercially purified by affinity chromatography) were suspended into phosphate buff...
More data for this Ligand-Target Pair
Target Info
PDB
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Target
Cholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 800nM
Assay Description:
Inhibition of human plasma BChE after 5 mins by Ellman's method
More data for this Ligand-Target Pair
Target Info
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Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.40E+3nM
Assay Description:
Inhibition of AChE (unknown origin) using ACh chloride as substrate preincubated for 15 mins before substrate addition by Ellman method
More data for this Ligand-Target Pair
Target Info
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Target
Cholinesterase
(Equus caballus (Horse))
University Of Life Sciences
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.93E+3nM
Assay Description:
Inhibition of equine BuChE by Ellman's method
More data for this Ligand-Target Pair
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Target
Acetylcholinesterase
(Rattus norvegicus (rat))
University Of Mysore
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 3.17E+3nM
Assay Description:
Inhibition of AChE in rat brain Striatum
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Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 6.00E+3nM
Assay Description:
Inhibition of electrical eel AChE using acetylthiocholine chloride as substrate incubated for 5 mins by DTNB reagent based Ellman's method
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 7.50E+3nM
Assay Description:
Inhibition of electric eel AChE by Ellman's method
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 1.42E+4nM
Assay Description:
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after ...
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Target
Cholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 1.63E+4nM
Assay Description:
Inhibition of human BChE by Ellman's method
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.63E+4nM
Assay Description:
Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 15...
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 1.93E+4nM
pH: 8.0
Assay Description:
Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Copy InChI
Affinity Data
IC50: 2.20E+4nM
Assay Description:
Inhibition of electric eel acetylcholinesterase using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after ...
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 2.22E+4nM
Assay Description:
Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 2.22E+4nM
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Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.22E+4nM
pH: 8.0 T: 2°C
Assay Description:
A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...
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Target
Cholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 2.61E+4nM
Assay Description:
Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after 15 mins by Ellman's me...
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.83E+4nM
Assay Description:
Inhibition of electric eel AChE by Ellman's method
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Copy BDB DOI
Target
Acetylcholinesterase
(Rattus norvegicus (rat))
University Of Mysore
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 3.72E+4nM
Assay Description:
Inhibition of AChE in rat brain Cerebellum
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Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
TBA
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Copy InChI
Affinity Data
IC50: 4.11E+4nM
Assay Description:
Inhibition of electric eel AchE
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Copy BDB DOI
Target
Carboxylic ester hydrolase
(Equus caballus (Horse))
University Of Life Sciences
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 4.32E+4nM
pH: 8.0
Assay Description:
Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...
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Target
Cholinesterase
(Homo sapiens (Human))
Comsats Institute Of Information Technology
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 4.91E+4nM
Assay Description:
Inhibition of human BChE using butyrylthiocholine iodide as substrate preincubated for 10 mins before substrate addition after 15 mins by Ellman's me...
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Copy BDB DOI
Target
Carboxylic ester hydrolase
(Equus caballus (Horse))
University Of Life Sciences
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 4.96E+4nM
pH: 8.0 T: 2°C
Assay Description:
A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...
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Target
Cholinesterase
(Equus caballus (Horse))
University Of Life Sciences
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 4.96E+4nM
Assay Description:
Inhibition of BuChE in equine serum using butyrylthiocholine chloride as substrate preincubated with enzyme for 10 mins prior to substrate challenge ...
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Target
Carboxylic ester hydrolase
(Equus caballus (Horse))
University Of Life Sciences
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 4.96E+4nM
Assay Description:
Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...
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Target
Cholinesterase
(Equus caballus (Horse))
University Of Life Sciences
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: 9.27E+4nM
Assay Description:
Inhibition of horse serum BChE incubated for 5 mins by DTNB reagent based Ellman's method
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Target
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
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Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
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Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
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Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
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Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
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Affinity Data
IC50: >1.35E+5nM
Assay Description:
Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...
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Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50022775
((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+6nM
Assay Description:
Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...
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