Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of M£Nster

Curated by ChEMBL

LigandBDBM50432844(CHEMBL2376223)Copy SMILESCopy InChI

Affinity DataIC50:  11nMAssay Description:Inhibition of FAAH in Sprague-Dawley rat brain microsomes assessed as N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide conversion to 4-pyren-1-ylbutanoic ac...More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMonoglyceride lipase(Homo sapiens (Human))
University Of M£Nster

Curated by ChEMBL

LigandBDBM50432844(CHEMBL2376223)Copy SMILESCopy InChI

Affinity DataIC50:  75nMAssay Description:Inhibition of human recombinant MAGL-mediated 1,3-dihydroxypropan-1-yl 4-pyren-1-ylbutanoate conversion to 4-pyren-1-ylbutanoic acid preincubated for...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI