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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Serine/threonine-protein kinase MARK1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389121
(CHEMBL2064628)
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Affinity Data
IC50: 115nM
Assay Description:
Inhibition of MARK1
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389121
(CHEMBL2064628)
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Affinity Data
IC50: 170nM
Assay Description:
Inhibition of Erk2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389121
(CHEMBL2064628)
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Affinity Data
IC50: 227nM
Assay Description:
Inhibition of GSK3beta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Cyclin-dependent kinase 2
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389121
(CHEMBL2064628)
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Affinity Data
IC50: 450nM
Assay Description:
Inhibition of CDK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase PAK 4
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50389121
(CHEMBL2064628)
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Copy InChI
Affinity Data
EC50: 4nM
Assay Description:
Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI