Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetSerine/threonine-protein kinase MARK1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataIC50:  115nMAssay Description:Inhibition of MARK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataIC50:  170nMAssay Description:Inhibition of Erk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataIC50:  227nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataIC50:  450nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50389121(CHEMBL2064628)
Affinity DataEC50:  4nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed