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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Court Of The University Of St Andrews

US Patent
LigandPNGBDBM50363783(CHEMBL1945265 | US9365508, 361a (3-Br, 4 tBu))
Affinity DataIC50:  4.60E+3nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Court Of The University Of St Andrews

US Patent
LigandPNGBDBM50363783(CHEMBL1945265 | US9365508, 361a (3-Br, 4 tBu))
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of recombinant human SitT2 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50363783(CHEMBL1945265 | US9365508, 361a (3-Br, 4 tBu))
Affinity DataIC50:  1.83E+4nMAssay Description:Inhibition of recombinant human SitT1 by Fluor de Lys fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of St. Andrews

Curated by ChEMBL
LigandPNGBDBM50363783(CHEMBL1945265 | US9365508, 361a (3-Br, 4 tBu))
Affinity DataIC50:  1.83E+4nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair
In DepthDetails US Patent