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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324527(4-[(8-Dimethylaminooctyl)-(hydroxyl)amino]-4-oxobu...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2C expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4A(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324527(4-[(8-Dimethylaminooctyl)-(hydroxyl)amino]-4-oxobu...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of recombinant His-tagged JMJD2A expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells by formaldehyde dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324527(4-[(8-Dimethylaminooctyl)-(hydroxyl)amino]-4-oxobu...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant PHD2 expressed in Sf9 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProlyl hydroxylase EGLN2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50324527(4-[(8-Dimethylaminooctyl)-(hydroxyl)amino]-4-oxobu...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant PHD1 expressed in Sf9 cells by time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed