Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL

LigandBDBM50259496((1R,9S,10S,11S)-12-[4-(4-Chloro-phenyl)-5-phenyl-t...)Copy SMILESCopy InChI

Affinity DataKi:  1.30E+3nMAssay Description:Displacement of fluorescently-tagged BH3 peptide from Bcl-2 (unknown origin) by chemiluminescent nitrogen detection methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBcl-2-like protein 1(Homo sapiens (Human))
Infinity Pharmaceuticals

Curated by ChEMBL

LigandBDBM50259496((1R,9S,10S,11S)-12-[4-(4-Chloro-phenyl)-5-phenyl-t...)Copy SMILESCopy InChI

Affinity DataKi:  6.60E+3nMAssay Description:Displacement of fluorescently-tagged BH3 peptide from Bcl-XL (unknown origin) by chemiluminescent nitrogen detection methodMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI