Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Muscarinic acetylcholine receptor M2
(RAT)
University Of South Carolina
Curated by
ChEMBL
Ligand
BDBM50004653
(CHEMBL106348 | N-(2-Dimethylamino-ethyl)-N'-[2-(5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 380nM
Assay Description:
Inhibition of [3H]-N-methylscopolamine to rat muscarinic acetylcholine receptor M2 from heart tissue
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
University Of South Carolina
Curated by
ChEMBL
Ligand
BDBM50004653
(CHEMBL106348 | N-(2-Dimethylamino-ethyl)-N'-[2-(5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 520nM
Assay Description:
In vitro inhibition of human acetylcholinesterase.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Muscarinic acetylcholine receptor M1
(Mus musculus)
University Of South Carolina
Curated by
ChEMBL
Ligand
BDBM50004653
(CHEMBL106348 | N-(2-Dimethylamino-ethyl)-N'-[2-(5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 670nM
Assay Description:
Inhibition of [3H]-pirenzepine binding to mouse muscarinic acetylcholine receptor M1 from cerebral cortex
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
University Of South Carolina
Curated by
ChEMBL
Ligand
BDBM50004653
(CHEMBL106348 | N-(2-Dimethylamino-ethyl)-N'-[2-(5-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.40E+3nM
Assay Description:
In vitro inhibition of human butryl cholinesterase.
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI