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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Rho-associated protein kinase 2
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50324578
((R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-...)
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Affinity Data
IC50: 6nM
Assay Description:
Inhibition of ROCK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Rho-associated protein kinase 2
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50324578
((R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 15nM
Assay Description:
Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Rho-associated protein kinase 1
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50324578
((R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-...)
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Copy InChI
Affinity Data
IC50: 33nM
Assay Description:
Inhibition of ROCK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase MRCK alpha
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50324578
((R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-...)
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Affinity Data
IC50: 333nM
Assay Description:
Inhibition of MRCKalpha
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 10
(Homo sapiens (Human))
The Scripps Research Institute
Curated by
ChEMBL
Ligand
BDBM50324578
((R)-N-(2-(2-(Dimethylamino)ethoxy)-5-fluoro-4-(1H-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >2.00E+4nM
Assay Description:
Inhibition of JNK3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI