Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50115808(CHEMBL61616 | Dimethyl-[2-(pyridin-3-yloxy)-ethyl]...)
Affinity DataKi:  21nMAssay Description:Binding affinity towards nicotinic acetylcholine receptor alpha4-beta2 from rat brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50115808(CHEMBL61616 | Dimethyl-[2-(pyridin-3-yloxy)-ethyl]...)
Affinity DataKi:  21nMAssay Description:Affinity to alpha-4-beta-2 AChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50115808(CHEMBL61616 | Dimethyl-[2-(pyridin-3-yloxy)-ethyl]...)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]nicotine from Homo sapiens (human) alpha4beta2 nicotinic acetylcholine receptor expressed in Homo sapiens (human) SH-EP1 cells af...More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50115808(CHEMBL61616 | Dimethyl-[2-(pyridin-3-yloxy)-ethyl]...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]iodo-MLA from alpha-7 nAChR in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed