Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
18
hits in this display
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.760nM
Assay Description:
In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1D receptor using [3H]-5-CT radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 0.920nM
Assay Description:
Binding affinity to recombinant human 5-hydroxytryptamine 1D receptor alpha
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4nM
Assay Description:
Binding affinity for cloned human 5-hydroxytryptamine 1D receptor beta
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.20nM
Assay Description:
In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1B receptor using [3H]-5-CT radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 79nM
Assay Description:
Binding affinity for cloned human 5-hydroxytryptamine 1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 124nM
Assay Description:
In vitro binding affinity was determined towards cloned human 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.80nM
Assay Description:
Binding affinity in CHO-K1 cells transfected with human 5-hydroxytryptamine 1D receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.20nM
Assay Description:
Binding affinity in CHO-K1 cells transfected with human recombinant 5-hydroxytryptamine 1B receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 4
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Bile salt export pump
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 2
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-binding cassette sub-family C member 3
(Homo sapiens (Human))
Amgen
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.33E+5nM
Assay Description:
Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.5nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 1D receptor beta using rabbit saphenous vein assay.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.80nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 1 receptor using rabbit jugular vein assay in the absence of endothelium
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 16nM
Assay Description:
Effective concentration of the compound determined by measuring inhibition of forskolin-stimulated c-AMP formation at 5-hydroxytryptamine 1B receptor...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(2) dopamine receptor
(Rattus norvegicus (rat))
Wellcome Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 0.0400nM
Assay Description:
Binding affinity against Dopamine receptor D2 in rat striatum using [3H]-spiperone as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Centre De Recherche Pierre Fabre
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 1.5nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 1D receptor beta using rabbit saphenous vein assay.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
Copy BDB DOI
Target
D(1A) dopamine receptor
(RAT)
Wellcome Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50033383
((S)-4-((3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)m...)
Copy SMILES
Copy InChI
Affinity Data
Kd: 0.300nM
Assay Description:
Binding affinity against dopamine receptor D1 in rat striatum using [3H]-SCH-23,390 as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI