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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

Target5-hydroxytryptamine receptor 1D(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50406758(CHEMBL39243)
Affinity DataIC50:  25nMAssay Description:Compound was tested for the displacement of [3H]-5-HT to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranesMore data for this Ligand-Target Pair
In DepthDetails Article
Target5-hydroxytryptamine receptor 1D(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50406758(CHEMBL39243)
Affinity DataIC50:  25nMAssay Description:Displacement of radioligand [3H]5-HT binding to 5-hydroxytryptamine 1D receptor in pig caudate membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1D(Sus scrofa)
TBA

Curated by ChEMBL
LigandPNGBDBM50406758(CHEMBL39243)
Affinity DataIC50:  25.1nMAssay Description:Binding activity against 5-hydroxytryptamine 3 receptor from rat cortex homogenate using [3H]-Q-ICS 205-930 as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406758(CHEMBL39243)
Affinity DataIC50:  316nMAssay Description:Displacement of [3H]8-OH-DPAT from pig cortex 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406758(CHEMBL39243)
Affinity DataIC50:  316nMAssay Description:Binding activity against 5-hydroxytryptamine 1A receptor from pig cortex membrane using [3H]8-OH-DPAT-HT as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerotonin 2 (5-HT2) receptor(RAT)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406758(CHEMBL39243)
Affinity DataIC50:  398nMAssay Description:Displacement of [3H]-Q-ICS 205-930 from rat cortex homogenate 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406758(CHEMBL39243)
Affinity DataIC50:  398nMAssay Description:Binding activity against 5-hydroxytryptamine 2C receptor from pig cortex membrane using [3H]mesulergine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406758(CHEMBL39243)
Affinity DataIC50:  1.26E+3nMAssay Description:Binding activity against 5-hydroxytryptamine 2C receptor from pig cortex membrane using [3H]mesulergine as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406758(CHEMBL39243)
Affinity DataIC50:  1.26E+3nMAssay Description:Displacement of [3H]mesulergine from pig cortex 5-hydroxytryptamine 1C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406758(CHEMBL39243)
Affinity DataIC50:  2.51E+3nMAssay Description:Displacement of [3H]-Q-ICS 205-930 from rat cortex homogenate 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rattus norvegicus)
Merck Sharp And Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50406758(CHEMBL39243)
Affinity DataIC50:  2.51E+3nMAssay Description:Inhibition of [3H]-Q-ICS 205-930 binding to rat cortex homogenate 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed