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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
5-hydroxytryptamine receptor 1F
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50106252
(CHEMBL263700 | [3-(2-Dimethylamino-ethyl)-5-hydrox...)
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Affinity Data
Ki: 29nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 1F receptor in CHO using [3H]-5-HT radioligand
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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CHEMBL
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Article
PubMed
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50106252
(CHEMBL263700 | [3-(2-Dimethylamino-ethyl)-5-hydrox...)
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Affinity Data
Ki: 54nM
Assay Description:
Binding affinity as displacement of [3H]-5-HT binding to 5-hydroxytryptamine 6 receptor in HeLa cells.
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50106252
(CHEMBL263700 | [3-(2-Dimethylamino-ethyl)-5-hydrox...)
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Affinity Data
Ki: 180nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 1D receptor in CHO cells using [3H]-5-HT as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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Ligand Info
CHEMBL
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Article
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Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50106252
(CHEMBL263700 | [3-(2-Dimethylamino-ethyl)-5-hydrox...)
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Affinity Data
Ki: 200nM
Assay Description:
Binding affinity for 5-hydroxytryptamine 2 receptor of rat cortical membrane using [3H]-DOB radioligand
More data for this Ligand-Target Pair
Target Info
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Target
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50106252
(CHEMBL263700 | [3-(2-Dimethylamino-ethyl)-5-hydrox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 420nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 1B receptor in CHO cells using [3H]-5-HT as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50106252
(CHEMBL263700 | [3-(2-Dimethylamino-ethyl)-5-hydrox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 620nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 1A receptor in HeLa cells was determined using [3H]-5-HT
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 7
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50106252
(CHEMBL263700 | [3-(2-Dimethylamino-ethyl)-5-hydrox...)
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Affinity Data
Ki: 1.60E+3nM
Assay Description:
Binding affinity for 5-hydroxytryptamine 7 receptor human cloned receptors in CHO cells using [3H]-5-HT
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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In Depth
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Article
PubMed
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Target
D(2) dopamine receptor
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50106252
(CHEMBL263700 | [3-(2-Dimethylamino-ethyl)-5-hydrox...)
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Affinity Data
Ki: >2.20E+3nM
Assay Description:
Binding affinity against dopamine receptor D2 using [3H]-spiperone radioligand in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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Article
PubMed
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Target
D(3) dopamine receptor
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50106252
(CHEMBL263700 | [3-(2-Dimethylamino-ethyl)-5-hydrox...)
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Affinity Data
Ki: >3.50E+3nM
Assay Description:
Binding affinity against dopamine receptor D3 in HEK 293 cells using [3H]-spiperone radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
D(4) dopamine receptor
(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50106252
(CHEMBL263700 | [3-(2-Dimethylamino-ethyl)-5-hydrox...)
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Affinity Data
Ki: >3.90E+3nM
Assay Description:
Binding affinity against dopamine receptor D4 cloned in HEK 293 cells using [3H]-spiperone radioligand
More data for this Ligand-Target Pair
Target Info
PDB
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KEGG
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In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 5A
(RAT)
Merck Sharp & Dohme Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50106252
(CHEMBL263700 | [3-(2-Dimethylamino-ethyl)-5-hydrox...)
Copy SMILES
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Affinity Data
Ki: 4.50E+3nM
Assay Description:
Binding affinity against 5-hydroxytryptamine 5A receptor in HEK 293 cells was determined using [3H]-LSD as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI