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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171261
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
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Affinity Data
Ki: 7nM
Assay Description:
Inhibition constant against human 5-hydroxytryptamine 2C receptor [INI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
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Ligand Info
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Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171261
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 33nM
Assay Description:
Inhibition constant against human 5-hydroxytryptamine 2C receptor [VGI isoforms] using [3H]-mesulergine as radioligand with the compound (10 uM) diss...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171261
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 38nM
Assay Description:
Inhibition constant against human 5-hydroxytryptamine 2B receptor using [3H]-LSD as radioligand with the compound (10 uM) dissolved in DMSO
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Rattus norvegicus (Rat))
Organix
Curated by
ChEMBL
Ligand
BDBM50171261
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 48nM
Assay Description:
Inhibition constant against rat 5-hydroxytryptamine 2C receptor using [3H]-mesulergine as radioligand with the compound (10 uM) dissolved in DMSO
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Rattus norvegicus (rat))
Organix
Curated by
ChEMBL
Ligand
BDBM50171261
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 590nM
Assay Description:
Inhibition constant against rat 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171261
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 900nM
Assay Description:
Inhibition constant against human 5-hydroxytryptamine 2A receptor using [3H]-ketanserin as radioligand with the compound (10 uM) dissolved in DMSO
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171261
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 9.5nM
Assay Description:
Modulation of human 5HT2C expressed in HEK293T cells co-transfected with Galphaq-RLuc8, Ggamma1-GFP2 and Gbeta1 assessed as dissociation of Galphaq f...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171261
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 32nM
Assay Description:
Modulation of human 5HT2B expressed in HEK293T cells co-transfected with Galphaq-RLuc8, Ggamma1-GFP2 and Gbeta1 assessed as dissociation of Galphaq f...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171261
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 86nM
Assay Description:
Modulation of human 5HT2A expressed in HEK293T cells co-transfected with Galphaq-RLuc8, Ggamma1-GFP2 and Gbeta1 assessed as dissociation of Galphaq f...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171261
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 633nM
Assay Description:
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2A receptor determi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Organix
Curated by
ChEMBL
Ligand
BDBM50171261
(3-(2-Dimethylamino-ethyl)-1-methyl-1H-indol-4-ol |...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 12nM
Assay Description:
Effective concentration required for accumulation of [3H]-inositol phosphate in cells stably expressing human 5-hydroxytryptamine 2C receptor determi...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI