Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ataturk University

LigandBDBM248149(CA standard inhibitor, 8)Copy SMILESCopy InChI

Affinity DataKi:  9.01E+3nM ΔG°:  -28.8kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandBDBM248149(CA standard inhibitor, 8)Copy SMILESCopy InChI

Affinity DataKi:  3.49E+4nM ΔG°:  -25.4kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCarbonic anhydrase(Saccharomyces cerevisiae (Baker's yeast))
Ataturk University

LigandBDBM248149(CA standard inhibitor, 8)Copy SMILESCopy InChI

Affinity DataKi:  9.01E+4nM ΔG°:  -23.1kJ/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI