Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL

LigandBDBM50198501((S)-5-(4-chlorophenyl)-N-(6-((dimethylamino)methyl...)Copy SMILESCopy InChI

Affinity DataKi:  11nMAssay Description:Functional antagonism of MCH-R1 expressed in HEK293 cellsMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL

LigandBDBM50198501((S)-5-(4-chlorophenyl)-N-(6-((dimethylamino)methyl...)Copy SMILESCopy InChI

Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of binding to hERGMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL

LigandBDBM50198501((S)-5-(4-chlorophenyl)-N-(6-((dimethylamino)methyl...)Copy SMILESCopy InChI

Affinity DataIC50:  5.60E+4nMAssay Description:Inhibition of binding to serotonin receptor 5HT2CMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI