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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302564
(CHEMBL577904 | N-(((cis)-4-(4-(dimethylamino)-5-me...)
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Affinity Data
IC50: 120nM
Assay Description:
Antagonist activity at CART form of human MCH1 receptor expressed in HEK293 cells coexpressing Galphaq assessed as inhibition of MCH-induced intracel...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Alpha-2A adrenergic receptor
(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302564
(CHEMBL577904 | N-(((cis)-4-(4-(dimethylamino)-5-me...)
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Affinity Data
IC50: 210nM
Assay Description:
Displacement of [3H]MK-912 from human adrenergic alpha2A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302564
(CHEMBL577904 | N-(((cis)-4-(4-(dimethylamino)-5-me...)
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Affinity Data
IC50: 320nM
Assay Description:
Displacement of [3H]rauwolsine from human 5HT2B receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Histamine H1 receptor
(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302564
(CHEMBL577904 | N-(((cis)-4-(4-(dimethylamino)-5-me...)
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Affinity Data
IC50: 920nM
Assay Description:
Displacement of [3H]pyrilamine from human histamine H1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Alpha-1A adrenergic receptor
(Homo sapiens (Human))
Arena Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50302564
(CHEMBL577904 | N-(((cis)-4-(4-(dimethylamino)-5-me...)
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Affinity Data
IC50: 3.60E+3nM
Assay Description:
Displacement of [3H]prazosin from human adrenergic alpha1A receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI