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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Neuropeptide Y receptor type 5
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50166563
(4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
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Affinity Data
IC50: 31nM
Assay Description:
Inhibitory activity against constitutively activated human Neuropeptide Y receptor Y5 stransiently expressed in COS-1 cells using [125I]-PYY
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Alpha-2A adrenergic receptor
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50166563
(4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
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Affinity Data
IC50: 47nM
Assay Description:
Inhibitory activity against constitutively activated human Alpha-2A adrenergic receptor transiently expressed in COS-1 cells using [3H]-MK912
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Alpha-2A adrenergic receptor
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50170184
(4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
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Affinity Data
IC50: 57nM
Assay Description:
Inhibitory activity against alpha-2A adrenergic receptor by using [3H]MK-912 as radioligand expressed in COS-1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50170184
(4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
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Affinity Data
IC50: 83nM
Assay Description:
Inhibitory activity against human CA-MCH-R1 (Melanin-concentrating hormone receptor 1) by using [125I](Phe13,Tyr19)MCH as radioligand expressed in HE...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuropeptide Y receptor type 5
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50170184
(4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 880nM
Assay Description:
Inhibitory activity against neuropeptide Y receptor type 5 by using [125I]PYY as radioligand expressed in COS-1 cells
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanin-concentrating hormone receptor 1
(Homo sapiens (Human))
Taisho Pharmaceutical
Curated by
ChEMBL
Ligand
BDBM50166563
(4-Bromo-N-[4-(4-dimethylamino-quinazolin-2-ylamino...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.20E+3nM
Assay Description:
Inhibitory activity against mutated constitutively activated human Melanin concentrating hormone receptor 1 (CA-MCH-R1) stably expressed in HEK293 ce...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI