Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081859((2R,3R)-2-((4-chloro-N-methylphenylsulfonamido)met...)
Affinity DataIC50:  4nMAssay Description:Inhibition of HNC MMP-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081859((2R,3R)-2-((4-chloro-N-methylphenylsulfonamido)met...)
Affinity DataIC50:  4nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
British Biotech Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50081859((2R,3R)-2-((4-chloro-N-methylphenylsulfonamido)met...)
Affinity DataIC50:  9nMAssay Description:Inhibition of HFC MMP-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50081859((2R,3R)-2-((4-chloro-N-methylphenylsulfonamido)met...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50081859((2R,3R)-2-((4-chloro-N-methylphenylsulfonamido)met...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Coll-3 MMP-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50081859((2R,3R)-2-((4-chloro-N-methylphenylsulfonamido)met...)
Affinity DataIC50:  30nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50081859((2R,3R)-2-((4-chloro-N-methylphenylsulfonamido)met...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Strom-1 MMP-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50081859((2R,3R)-2-((4-chloro-N-methylphenylsulfonamido)met...)
Affinity DataIC50:  100nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50081859((2R,3R)-2-((4-chloro-N-methylphenylsulfonamido)met...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Gel-A MMP-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed