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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Squalene--hopene cyclase
(Alicyclobacillus acidocaldarius)
Albert-Ludwigs-University Of Freiburg
Curated by
ChEMBL
Ligand
BDBM50128062
((4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMI...)
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Affinity Data
IC50: 18nM
Assay Description:
Inhibitory activity against squalene hopene cyclase from Alicyclobacillus acidocaldarius
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
DrugBank
MMDB
PDB
3D Structure (crystal)
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Target
Lanosterol synthase
(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by
ChEMBL
Ligand
BDBM50128062
((4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMI...)
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Affinity Data
IC50: 19nM
Assay Description:
Inhibitory activity against Oxidosqualene-lanosterol cyclase from human liver microsomes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lanosterol synthase
(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by
ChEMBL
Ligand
BDBM50128062
((4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMI...)
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Copy InChI
Affinity Data
IC50: 19.1nM
Assay Description:
Inhibition of oxidosqualene cyclase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lanosterol synthase ERG7
(Saccharomyces cerevisiae)
Università
Curated by
ChEMBL
Ligand
BDBM50128062
((4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMI...)
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Affinity Data
IC50: 180nM
Assay Description:
Inhibition of yeast OSC expressed in Saccharomyces cerevisiae SMY8
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cycloartenol synthase
(Arabidopsis thaliana)
Università
Curated by
ChEMBL
Ligand
BDBM50128062
((4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMI...)
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Affinity Data
IC50: 260nM
Assay Description:
Inhibition of Arabidopsis thaliana cycloartenol synthase expressed in Saccharomyces cerevisiae SMY8
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Lanosterol synthase
(Homo sapiens (Human))
Albert-Ludwigs-University Of Freiburg
Curated by
ChEMBL
Ligand
BDBM50128062
((4-BROMOPHENYL)[4-({(2E)-4-[CYCLOPROPYL(METHYL)AMI...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 270nM
Assay Description:
Inhibition of human OSC expressed in Saccharomyces cerevisiae SMY8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI