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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
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Target
Carboxylic ester hydrolase
(Equus caballus (Horse))
Teva Pharmaceutical Industries
Ligand
BDBM10761
(3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl ...)
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Affinity Data
IC50: 5.56E+3nM
Assay Description:
The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Amine oxidase [flavin-containing] B
(Rattus norvegicus (rat))
Teva Pharmaceutical Industries
Ligand
BDBM10761
(3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl ...)
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Affinity Data
IC50: 1.00E+4nM
Assay Description:
Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Teva Pharmaceutical Industries
Ligand
BDBM10761
(3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl ...)
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Affinity Data
IC50: 4.12E+4nM
Assay Description:
The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Amine oxidase [flavin-containing] A
(Rattus norvegicus (rat))
Teva Pharmaceutical Industries
Ligand
BDBM10761
(3-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-inden-5-yl ...)
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Copy InChI
Affinity Data
IC50: 1.70E+5nM
Assay Description:
Inhibition of MAO activity was determined by a radiometric procedure from Tipton and Youdim. Homogenized rat brain was used as the source of enzymes....
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI