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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359396(CHEMBL1929420 | US8999994, 5)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of rat liver mitochondrial MAO-A using [14C]-5-hydroxytryptamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359396(CHEMBL1929420 | US8999994, 5)
Affinity DataIC50:  130nMAssay Description:Inhibition of rat liver mitochondrial MAO-B using [14C]-phenylethylamine after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50359396(CHEMBL1929420 | US8999994, 5)
Affinity DataIC50:  420nMpH: 8.0Assay Description:The inhibitory activity of the enzyme acetylcholinesterase (AChE) was evaluated by the Ellman method (Biochem. Pharmacol. 1961, 7, 88) using an elect...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50359396(CHEMBL1929420 | US8999994, 5)
Affinity DataIC50:  420nMAssay Description:Inhibition of Electrophorus electricus AchE using acetylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
Consejo Superior De Investigaciones Cientificas

US Patent
LigandPNGBDBM50359396(CHEMBL1929420 | US8999994, 5)
Affinity DataIC50:  2.10E+3nMpH: 8.0Assay Description:The inhibitory activity of the enzyme acetylcholinesterase (AChE) was evaluated by the Ellman method (Biochem. Pharmacol. 1961, 7, 88) using an elect...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCholinesterase(Equus caballus (Horse))
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359396(CHEMBL1929420 | US8999994, 5)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of equine serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins measured after 15 mins of substrate addition b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359396(CHEMBL1929420 | US8999994, 5)
Affinity DataIC50:  6.70E+3nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of monoamine oxidases A and B was assessed by the Fowler and Tipton radiometric method (Biochem Pharmacol 1981, 30, 3329) usi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Universitat Aut£Noma De Barcelona

Curated by ChEMBL
LigandPNGBDBM50359396(CHEMBL1929420 | US8999994, 5)
Affinity DataIC50:  1.30E+5nMpH: 7.4 T: 2°CAssay Description:The inhibitory activity of monoamine oxidases A and B was assessed by the Fowler and Tipton radiometric method (Biochem Pharmacol 1981, 30, 3329) usi...More data for this Ligand-Target Pair
In DepthDetails US Patent