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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetAcetylcholinesterase(Rattus norvegicus (rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199520(CHEMBL397232 | N,N'-dimethyl-N,N'-bis[2-(1-oxo-8,1...)
Affinity DataIC50:  18.5nMpH: 5.0Assay Description:Inhibition of AChE in rat cortex at pH 5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10946((1R,10R)-16-methyl-14-{3-[methyl({8-[methyl({3-[(1...)
Affinity DataIC50:  18.5nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50199520(CHEMBL397232 | N,N'-dimethyl-N,N'-bis[2-(1-oxo-8,1...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of BuChE in rat serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Rattus norvegicus (rat))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM10946((1R,10R)-16-methyl-14-{3-[methyl({8-[methyl({3-[(1...)
Affinity DataIC50:  6.30E+4nMpH: 7.4 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed