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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
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Target
Acetylcholinesterase
(Rattus norvegicus (rat))
Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199520
(CHEMBL397232 | N,N'-dimethyl-N,N'-bis[2-(1-oxo-8,1...)
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Affinity Data
IC50: 18.5nM
pH: 5.0
Assay Description:
Inhibition of AChE in rat cortex at pH 5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Acetylcholinesterase
(Rattus norvegicus (rat))
Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM10946
((1R,10R)-16-methyl-14-{3-[methyl({8-[methyl({3-[(1...)
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Affinity Data
IC50: 18.5nM
pH: 7.4 T: 2°C
Assay Description:
The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carboxylic ester hydrolase
(Rattus norvegicus (rat))
Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM50199520
(CHEMBL397232 | N,N'-dimethyl-N,N'-bis[2-(1-oxo-8,1...)
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Affinity Data
IC50: 6.30E+4nM
Assay Description:
Inhibition of BuChE in rat serum
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Carboxylic ester hydrolase
(Rattus norvegicus (rat))
Chinese Academy Of Sciences
Curated by
ChEMBL
Ligand
BDBM10946
((1R,10R)-16-methyl-14-{3-[methyl({8-[methyl({3-[(1...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.30E+4nM
pH: 7.4 T: 2°C
Assay Description:
The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI