Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetSolute carrier family 22 member 3(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL

LigandBDBM50420232(CHEMBL2074900)Copy SMILESCopy InChI

Affinity DataIC50:  50nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 0.25 uM) in OCT3-expressing HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSolute carrier family 22 member 2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL

LigandBDBM50420232(CHEMBL2074900)Copy SMILESCopy InChI

Affinity DataIC50:  100nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 0.25 uM) in OCT2-expressing HEK293 cellsMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSolute carrier family 22 member 1(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL

LigandBDBM50420232(CHEMBL2074900)Copy SMILESCopy InChI

Affinity DataIC50: >300nMAssay Description:TP_TRANSPORTER: inhibition of MPP+ uptake (MPP+: 0.25 uM) in OCT1-expressing HEK293 cellsMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI