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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
C-X-C chemokine receptor type 2
(Homo sapiens (Human))
Syntrix Biosystems
Curated by
ChEMBL
Ligand
BDBM50115210
(CHEMBL3609011 | USRE47740, Compound 19 | USRE48547...)
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Affinity Data
IC50: 121nM
Assay Description:
Antagonist activity at CXCR2 (unknown origin) transfected in RBL cells assessed as inhibition of IL-8-mediated intracellular calcium release preincub...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
C-X-C chemokine receptor type 2
(Homo sapiens (Human))
Syntrix Biosystems
Curated by
ChEMBL
Ligand
BDBM50115210
(CHEMBL3609011 | USRE47740, Compound 19 | USRE48547...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 244nM
Assay Description:
An in vitro assay showed inhibition of CXCR2-mediated intracellular calcium release by treatment with compound 9 (IC50=586±91 nM). Briefly, human neu...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
C-X-C chemokine receptor type 2
(Homo sapiens (Human))
Syntrix Biosystems
Curated by
ChEMBL
Ligand
BDBM50115210
(CHEMBL3609011 | USRE47740, Compound 19 | USRE48547...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 244nM
Assay Description:
Briefly, human neutrophils were suspended in HBSS− (without Ca2+ and Mg2+) containing 10 mM HEPES and FLIPR Calcium 3 dye (3.1×107 cells in tot...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
C-X-C chemokine receptor type 1
(Homo sapiens (Human))
Syntrix Biosystems
Curated by
ChEMBL
Ligand
BDBM50115210
(CHEMBL3609011 | USRE47740, Compound 19 | USRE48547...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 681nM
Assay Description:
Antagonist activity at CXCR1 (unknown origin) transfected in RBL cells assessed as inhibition of IL-8-mediated intracellular calcium release preincub...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI