Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetHistamine H1 receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL

LigandBDBM50297870(CHEMBL551888 | N-benzyl-1-(1-(4-fluorobenzyl)-1H-b...)Copy SMILESCopy InChI

Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2D6(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL

LigandBDBM50297870(CHEMBL551888 | N-benzyl-1-(1-(4-fluorobenzyl)-1H-b...)Copy SMILESCopy InChI

Affinity DataKi:  805nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL

LigandBDBM50297870(CHEMBL551888 | N-benzyl-1-(1-(4-fluorobenzyl)-1H-b...)Copy SMILESCopy InChI

Affinity DataKi:  3.58E+3nMAssay Description:Displacement of [3H]N-methyl scopolamine from human muscarinic M1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI