Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetHistone deacetylase 4 [2-1084](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM187214(US9670193, 5 N-((2-chloropyridin-4-yl)methyl)-N-me...)
Affinity DataIC50:  40nMpH: 8.0 T: 2°CAssay Description:Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM187214(US9670193, 5 N-((2-chloropyridin-4-yl)methyl)-N-me...)
Affinity DataIC50:  1.70E+3nMAssay Description:Human recombinant full length HDAC1 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 6(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM187214(US9670193, 5 N-((2-chloropyridin-4-yl)methyl)-N-me...)
Affinity DataIC50:  2.10E+3nMAssay Description:Human recombinant full length HDAC6 expressed in a baculovirus expression system was purchased from BPS BioSciences (San Diego, Calif., U.S.A.). The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent