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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
E3 ubiquitin-protein ligase XIAP
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50441797
(CHEMBL2436327 | US10053431, 8)
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Affinity Data
IC50: 383nM
Assay Description:
Displacement of AVPIAQKSEK (epsilon-biotin)-OH from 6xhistidine-thrombin-TEV-tagged XIAP BIR2 domain (124 to 240) (unknown origin) after 45 mins by T...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
E3 ubiquitin-protein ligase XIAP [124-240]
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM50441797
(CHEMBL2436327 | US10053431, 8)
Copy SMILES
Copy InChI
Affinity Data
IC50: 383nM
pH: 7.5 T: 2°C
Assay Description:
Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
E3 ubiquitin-protein ligase XIAP [241-356]
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM50441797
(CHEMBL2436327 | US10053431, 8)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.48E+4nM
pH: 7.5 T: 2°C
Assay Description:
Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
E3 ubiquitin-protein ligase XIAP
(Homo sapiens (Human))
Hoffmann-La Roche
Curated by
ChEMBL
Ligand
BDBM50441797
(CHEMBL2436327 | US10053431, 8)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.48E+4nM
Assay Description:
Displacement of AVPIAQKSEK (epsilon-biotin)-OH from 6xhistidine-thrombin-TEV-tagged XIAP BIR3 domain (241 to 356) (unknown origin) after 45 mins by T...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI