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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetAcetylcholine-binding protein(Lymnaea stagnalis)
University Of California San Diego

LigandPNGBDBM91630(15t | alpha7 agonists 15t)
Affinity DataKi:  40nM ΔG°:  -41.5kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSoluble acetylcholine receptor(Aplysia Californica)
University Of California San Diego

LigandPNGBDBM91630(15t | alpha7 agonists 15t)
Affinity DataKi:  110nM ΔG°:  -39.1kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSoluble acetylcholine receptor(Aplysia Californica)
University Of California San Diego

LigandPNGBDBM91630(15t | alpha7 agonists 15t)
Affinity DataKi:  140nM ΔG°:  -38.5kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSoluble acetylcholine receptor(Aplysia Californica)
University Of California San Diego

LigandPNGBDBM91630(15t | alpha7 agonists 15t)
Affinity DataKi:  240nM ΔG°:  -37.2kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4(Homo sapiens (Human))
University Of California San Diego

LigandPNGBDBM91630(15t | alpha7 agonists 15t)
Affinity DataKi:  3.20E+4nM ΔG°:  -26.7kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Mus musculus (house mouse))
University Of California San Diego

LigandPNGBDBM91630(15t | alpha7 agonists 15t)
Affinity DataKi:  3.20E+4nM ΔG°:  -26.7kJ/molepH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of California San Diego

LigandPNGBDBM91630(15t | alpha7 agonists 15t)
Affinity DataEC50:  1.20E+4nMpH: 7.4 T: 2°CAssay Description:Assay Description 2 Assays used to generate Ki or EC50 values. 1) SPA Assay - Quick screen binding assays were performed using 100 ?l of 0.2 mg/ml an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed