Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50260280((S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50:  150nMAssay Description:Inhibition of Eg5 basal ATPase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50260280((S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50:  520nMAssay Description:Inhibition of basal ATPase activity of human Eg5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50260280((S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50:  520nMAssay Description:Inhibition of Eg5 assessed as inhibition of microtubule-induced ATPase activity (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50260280((S)-(4-(3-hydroxyphenyl)-1,6-dimethyl-2-thioxo-1,2...)
Affinity DataIC50:  650nMAssay Description:Inhibition of microtubule-stimulated human Eg5 ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed