Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 6 hits in this display
BDBM113278(US10336717, Compound 418 | US8633212, 56 | US92121...)
BDBM113278(US10336717, Compound 418 | US8633212, 56 | US92121...)
IC50: 8.70nMAssay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
BDBM113278(US10336717, Compound 418 | US8633212, 56 | US92121...)
IC50: 33.8nMAssay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
BDBM113278(US10336717, Compound 418 | US8633212, 56 | US92121...)
IC50: 204nMAssay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
BDBM113278(US10336717, Compound 418 | US8633212, 56 | US92121...)
BDBM113278(US10336717, Compound 418 | US8633212, 56 | US92121...)