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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Emory University
Curated by
ChEMBL
Ligand
BDBM50431028
(CHEMBL2338333)
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Affinity Data
IC50: 1.30E+3nM
Assay Description:
Inhibition of recombinant KDR (unknown origin) by FRET-based Z'-LYTE assay
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Target Info
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Target
RAC-beta serine/threonine-protein kinase
(Homo sapiens (Human))
Emory University
Curated by
ChEMBL
Ligand
BDBM50431028
(CHEMBL2338333)
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Affinity Data
IC50: 1.90E+3nM
Assay Description:
Inhibition of recombinant AKT2 (unknown origin) by FRET-based Z'-LYTE assay
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Target
5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1
(Homo sapiens (Human))
Emory University
Curated by
ChEMBL
Ligand
BDBM50431028
(CHEMBL2338333)
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Affinity Data
IC50: 2.50E+3nM
Assay Description:
Inhibition of recombinant AMPK A1/B1/G1 (unknown origin) by FRET-based Z'-LYTE assay
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Target Info
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Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
Emory University
Curated by
ChEMBL
Ligand
BDBM50431028
(CHEMBL2338333)
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Affinity Data
IC50: 2.60E+3nM
Assay Description:
Inhibition of recombinant AKT1 (unknown origin) by FRET-based Z'-LYTE assay
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Target Info
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Target
Serine/threonine-protein kinase Nek1
(Homo sapiens (Human))
Emory University
Curated by
ChEMBL
Ligand
BDBM50431028
(CHEMBL2338333)
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Affinity Data
IC50: 3.50E+3nM
Assay Description:
Inhibition of recombinant NEK1 (unknown origin) by FRET-based Z'-LYTE assay
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Target Info
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Target
Inhibitor of nuclear factor kappa-B kinase subunit beta
(Homo sapiens (Human))
Emory University
Curated by
ChEMBL
Ligand
BDBM50431028
(CHEMBL2338333)
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Affinity Data
IC50: 4.00E+3nM
Assay Description:
Inhibition of recombinant IKBKB (unknown origin) by FRET-based Z'-LYTE assay
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Target Info
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Target
Ribosomal protein S6 kinase beta-1
(Homo sapiens (Human))
Emory University
Curated by
ChEMBL
Ligand
BDBM50431028
(CHEMBL2338333)
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Affinity Data
IC50: 6.00E+3nM
Assay Description:
Inhibition of recombinant RPS6K1 (unknown origin) by FRET-based Z'-LYTE assay
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Target Info
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Target
RAF proto-oncogene serine/threonine-protein kinase
(Homo sapiens (Human))
Emory University
Curated by
ChEMBL
Ligand
BDBM50431028
(CHEMBL2338333)
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Affinity Data
IC50: 6.50E+3nM
Assay Description:
Inhibition of recombinant RAF1 (unknown origin) by cascade reaction assay
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Target Info
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Target
Dual specificity mitogen-activated protein kinase kinase 1
(Homo sapiens (Human))
Emory University
Curated by
ChEMBL
Ligand
BDBM50431028
(CHEMBL2338333)
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Affinity Data
IC50: 9.00E+3nM
Assay Description:
Inhibition of recombinant MEK1 (unknown origin) by cascade reaction assay
More data for this Ligand-Target Pair
Target Info
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Target
MAP kinase-activated protein kinase 2
(Homo sapiens (Human))
Emory University
Curated by
ChEMBL
Ligand
BDBM50431028
(CHEMBL2338333)
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Affinity Data
IC50: 9.80E+3nM
Assay Description:
Inhibition of recombinant MAPKAPK2 (unknown origin) by FRET-based Z'-LYTE assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Emory University
Curated by
ChEMBL
Ligand
BDBM50431028
(CHEMBL2338333)
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Affinity Data
IC50: 2.70E+4nM
Assay Description:
Inhibition of recombinant ERK2 (unknown origin) by FRET-based Z'-LYTE assay
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Target Info
PDB
MMDB
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KEGG
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Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Emory University
Curated by
ChEMBL
Ligand
BDBM50431028
(CHEMBL2338333)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of recombinant MAPK14 (unknown origin) by FRET-based Z'-LYTE assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
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In Depth
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Article
PubMed
Copy BDB DOI