Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50:  58nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50:  390nMAssay Description:Inhibition of PDK1 assessed as [gamma-33P]ATP incorporation into substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
S*Bio

Curated by ChEMBL
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50:  390nMAssay Description:Inhibition of PDK1 using [gamma33P]-ATP as substrate after 30 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50:  450nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
S Bio

Curated by ChEMBL
LigandPNGBDBM50360581(CHEMBL1933344)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed