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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM10686((-)-N1-norphenserine | (3aS)-3a,8-dimethyl-1H,2H,3...)
Affinity DataIC50:  13.8nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM10686((-)-N1-norphenserine | (3aS)-3a,8-dimethyl-1H,2H,3...)
Affinity DataIC50:  612nMAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. The absorbance changes at 412 nm were recorded for 5 min with ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

LigandPNGBDBM476174((−)-N1-norphenylcarbamoyleseroline | US10864...)
Affinity DataEC50:  62nMAssay Description:To address these issues, the present disclosure relates to the development and utilization of a (−)-phenserine extended release formulation. To...More data for this Ligand-Target Pair
In DepthDetails US Patent