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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 20 hits in this display   

TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  1.40nMAssay Description:Antagonism against bradykinin receptor B2 in guinea pig ileal tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  2.80nMAssay Description:The compound tested for agonistic activity against Opioid receptor delta 1 using [3H]- NT1 as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of [3H]-NTI binding to Opioid receptor delta 1 from mouse brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  3.30nMAssay Description:Selective binding affinity against Opioid receptor delta 2, using [3H]DSLET as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]- diprenorphine from mu-W318A-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]- diprenorphine from delta receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  10.6nMAssay Description:Displacement of [3H]DAMGO from Hartley guinea pig mu opioid receptor by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  11nMAssay Description:selective binding affinity against mu opioid receptor, using [3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  14nMAssay Description:Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from mouse brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  14nMAssay Description:The compound tested for agonistic activity against Opioid receptor mu 1 using [3H]- DAMGO as the radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  46.6nMAssay Description:Displacement of [3H]- diprenorphine from delta-W284E-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]diprenorphine from k-Y312A-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  88.4nMAssay Description:Displacement of [3H]- diprenorphine from mu-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  154nMAssay Description:Displacement of [3H]- diprenorphine from mu-K303E-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  292nMAssay Description:Displacement of [3H]diprenorphine from k-E297A-receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  488nMAssay Description:Displacement of [3H]diprenorphine from opioid receptor kappa 1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  588nMAssay Description:Displacement of [3H]U69493 from Hartley guinea pig kappa opioid receptor by liquid scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi:  588nMAssay Description:selective binding affinity against kappa opioid receptor, using [3H]U-69593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi: >3.00E+3nMAssay Description:The compound tested for agonistic activity against Opioid receptor kappa 1 as the [3H]- U-69,594 radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mus musculus (Mouse))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50297170(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1 from mouse brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed