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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
20
hits in this display
Target
Delta-type opioid receptor
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
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Affinity Data
Ki: 1.40nM
Assay Description:
Antagonism against bradykinin receptor B2 in guinea pig ileal tissue
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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Article
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Target
Delta-type opioid receptor
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
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Affinity Data
Ki: 2.80nM
Assay Description:
The compound tested for agonistic activity against Opioid receptor delta 1 using [3H]- NT1 as the radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
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Target
Delta-type opioid receptor
(MOUSE)
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
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Affinity Data
Ki: 2.80nM
Assay Description:
Inhibition of [3H]-NTI binding to Opioid receptor delta 1 from mouse brain membranes.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
PubMed
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Target
Delta-type opioid receptor
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 3.30nM
Assay Description:
Selective binding affinity against Opioid receptor delta 2, using [3H]DSLET as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
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Affinity Data
Ki: 3.90nM
Assay Description:
Displacement of [3H]- diprenorphine from mu-W318A-receptor expressed in HEK 293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(MOUSE)
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 4.10nM
Assay Description:
Displacement of [3H]- diprenorphine from delta receptor expressed in HEK 293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(GUINEA PIG)
Kitasato University
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
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Affinity Data
Ki: 10.6nM
Assay Description:
Displacement of [3H]DAMGO from Hartley guinea pig mu opioid receptor by liquid scintillation counter
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(GUINEA PIG)
Kitasato University
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 11nM
Assay Description:
selective binding affinity against mu opioid receptor, using [3H]DAMGO as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(MOUSE)
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 14nM
Assay Description:
Inhibition of [3H]-DAMGO binding to Opioid receptor mu 1 from mouse brain membranes.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 14nM
Assay Description:
The compound tested for agonistic activity against Opioid receptor mu 1 using [3H]- DAMGO as the radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(MOUSE)
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 46.6nM
Assay Description:
Displacement of [3H]- diprenorphine from delta-W284E-receptor expressed in HEK 293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Rattus norvegicus (rat))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 55nM
Assay Description:
Displacement of [3H]diprenorphine from k-Y312A-receptor expressed in HEK 293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 88.4nM
Assay Description:
Displacement of [3H]- diprenorphine from mu-receptor expressed in HEK 293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Rattus norvegicus (rat))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 154nM
Assay Description:
Displacement of [3H]- diprenorphine from mu-K303E-receptor expressed in HEK 293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Rattus norvegicus (rat))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 292nM
Assay Description:
Displacement of [3H]diprenorphine from k-E297A-receptor expressed in HEK 293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Rattus norvegicus (rat))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 488nM
Assay Description:
Displacement of [3H]diprenorphine from opioid receptor kappa 1 expressed in HEK 293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 588nM
Assay Description:
Displacement of [3H]U69493 from Hartley guinea pig kappa opioid receptor by liquid scintillation counter
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 588nM
Assay Description:
selective binding affinity against kappa opioid receptor, using [3H]U-69593 as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >3.00E+3nM
Assay Description:
The compound tested for agonistic activity against Opioid receptor kappa 1 as the [3H]- U-69,594 radioligand.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Mus musculus (Mouse))
University Of Minnesota
Curated by
ChEMBL
Ligand
BDBM50297170
(7-(2'-spiroindanyl)oxymorphone | 7-(Spiroindano)Ox...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >3.00E+3nM
Assay Description:
Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1 from mouse brain membranes.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI