Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50099563
(CHEMBL21553 | boron-containing nicotine analogue)
Copy SMILES
Copy InChI
Affinity Data
Ki: 600nM
Assay Description:
Affinity for alpha-7 neuronal nicotinic acetylcholine receptor subtype determined by inhibition of [3H]-MLA binding to rat brain membranes
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat))
University Of Florida
Curated by
ChEMBL
Ligand
BDBM50170269
((2R,6S)-12-(cyanoboranyl)-3-methyl-3,12-diazatricy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 600nM
Assay Description:
Inhibition of [3H]-Nicotine binding to alpha4-beta2 nicotinic acetylcholine receptor of rat brain membrane
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-3/beta-2
(Rattus norvegicus (Rat))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50099563
(CHEMBL21553 | boron-containing nicotine analogue)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.40E+3nM
Assay Description:
Affinity for Nicotinic acetylcholine receptor alpha4-beta2 tested by analogue-induced inhibition of [3H]NIC binding to rat striatal membranes
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50170269
((2R,6S)-12-(cyanoboranyl)-3-methyl-3,12-diazatricy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 2.40E+3nM
Assay Description:
Inhibition of [3H]-MLA binding to rat alpha7 nicotinic acetylcholine receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat))
University Of Kentucky
Curated by
ChEMBL
Ligand
BDBM50170269
((2R,6S)-12-(cyanoboranyl)-3-methyl-3,12-diazatricy...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.00E+4nM
Assay Description:
Effective concentration against rat alpha7 nicotinic acetylcholine receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI