Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 13 hits in this display   

Target5-hydroxytryptamine 1D receptor(Bos taurus (Bovine))
Neuraxon

US Patent
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50:  50nMAssay Description:5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50:  550nMAssay Description:Inhibition of human nNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50:  1.78E+3nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of rat nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50:  9.52E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50:  2.05E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50:  3.61E+4nMAssay Description:Inhibition of human eNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50:  5.40E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

US Patent
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50:  5.80E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

US Patent
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50:  5.85E+4nMAssay Description:Inhibition of human iNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106699(CHEMBL1957350 | US8586620, 46)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed