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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Universitat De Barcelona
Ligand
BDBM34147
(CHEMBL425196 | pyrrolidinylindole, 6)
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Affinity Data
Ki: 1nM ΔG°: -53.4kJ/mole EC50: 53.3nM
pH: 7.4 T: 2°C
Assay Description:
Radioligand binding assays were performed using membranes from HEK-293 transfected with human 5-HT6 receptor. In these membranes the receptor concent...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
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Article
PubMed
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Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Universitat De Barcelona
Ligand
BDBM34147
(CHEMBL425196 | pyrrolidinylindole, 6)
Copy SMILES
Copy InChI
Affinity Data
Ki: 1nM
Assay Description:
Displacement of [3H]-LSD from cloned human 5-hydroxytryptamine 6 receptor expressed in HeLa cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 6
(Homo sapiens (Human))
Universitat De Barcelona
Ligand
BDBM34147
(CHEMBL425196 | pyrrolidinylindole, 6)
Copy SMILES
Copy InChI
Affinity Data
IC50: 53.3nM
Assay Description:
Inhibition of cAMP production in HeLa cells expressing human 5-HT6 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI