BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 474.5
BDBM50264297

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
B1 bradykinin receptor


(Macaca fascicularis)
BDBM50264297
PNG
(1-benzyl-N-(2-(4-(1-methylpiperidin-4-yl)piperazin...)
Show SMILES CN1CCC(CC1)N1CCN(CC1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1
Show InChI InChI=1S/C27H34N6O2/c1-30-13-11-22(12-14-30)31-15-17-32(18-16-31)25(34)19-28-27(35)26-29-23-9-5-6-10-24(23)33(26)20-21-7-3-2-4-8-21/h2-10,22H,11-20H2,1H3,(H,28,35)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 686n/an/an/an/an/an/a



Neurogen Corporation

Curated by ChEMBL


Assay Description
Antagonist activity at Cynomolgus monkey bradykinin B1 receptor expressed in CHO cells assessed as calcium transient by FLIPR assay


Bioorg Med Chem Lett 18: 5027-31 (2008)


Article DOI: 10.1016/j.bmcl.2008.08.014
BindingDB Entry DOI: 10.7270/Q2NG4QDX
More data for this
Ligand-Target Pair