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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Mitogen-activated protein kinase 14
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50315133
(4-(5-(1-methylpiperidin-4-yl)-3-(4-(trifluoromethy...)
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Affinity Data
IC50: 40.5nM
Assay Description:
Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Mitogen-activated protein kinase 11
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50315133
(4-(5-(1-methylpiperidin-4-yl)-3-(4-(trifluoromethy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.77E+3nM
Assay Description:
Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI