Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

Target5-hydroxytryptamine 1D receptor(Bos taurus (Bovine))
Neuraxon

US Patent
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50:  570nMAssay Description:5-HT1D binding assays (agonist radioligand)were performed using bovine caudate membranes according to the methods of Heuring and Peroutka (J. Neurosc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of human nNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50:  1.88E+3nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50:  2.42E+4nMAssay Description:Inhibition of human eNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50:  3.26E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

US Patent
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50:  5.80E+4nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Neuraxon

US Patent
LigandPNGBDBM106697(CHEMBL1957353 | US8586620, 43)
Affinity DataIC50:  5.82E+4nMAssay Description:Inhibition of human iNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine to [3H]-L-citrullineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed