Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetNociceptin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]enadoline from human kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataKi: >500nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataEC50:  2.19E+3nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataEC50:  67nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255898(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Affinity DataEC50:  70nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed