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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Nociceptin receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50255898
(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
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Affinity Data
Ki: 0.200nM
Assay Description:
Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Mu-type opioid receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50255898
(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
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Affinity Data
Ki: 3.70nM
Assay Description:
Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHOK1 cells
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50255898
(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
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Copy InChI
Affinity Data
Ki: 25nM
Assay Description:
Displacement of [3H]enadoline from human kappa opioid receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50255898
(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >500nM
Assay Description:
Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHOK1 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50255898
(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.19E+3nM
Assay Description:
Agonist activity at human delta opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nociceptin receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50255898
(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.40nM
Assay Description:
Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50255898
(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 67nM
Assay Description:
Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50255898
(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 70nM
Assay Description:
Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS binding
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI