Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile

Curated by ChEMBL
LigandPNGBDBM50433568(CHEMBL2381564)
Affinity DataKi:  151nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile

Curated by ChEMBL
LigandPNGBDBM50433568(CHEMBL2381564)
Affinity DataKi:  2.93E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Homo sapiens (Human))
University Of Chile

Curated by ChEMBL
LigandPNGBDBM50433568(CHEMBL2381564)
Affinity DataIC50:  528nMAssay Description:Displacement of [3H]cytisine from human alpha4beta2 nAChR overexpressed in human SHEP cells after 75 mins by liquid scintillation spectrometric analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
University Of Chile

Curated by ChEMBL
LigandPNGBDBM50433568(CHEMBL2381564)
Affinity DataIC50:  5.85E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from human alpha7 nAChR overexpressed in human SH-SY5Y cells after 120 mins by liquid scintillation spectrom...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed