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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Histamine H1 receptor
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50316936
(2-(1-methylpiperidin-3-yl)-1-(2-phenoxyethyl)-1H-b...)
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Affinity Data
Ki: 0.800nM
Assay Description:
Antagonist activity at histamine H1 receptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50316936
(2-(1-methylpiperidin-3-yl)-1-(2-phenoxyethyl)-1H-b...)
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Affinity Data
Ki: 40nM
Assay Description:
Inhibition of muscarinic M1 receptor
More data for this Ligand-Target Pair
Target Info
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50316936
(2-(1-methylpiperidin-3-yl)-1-(2-phenoxyethyl)-1H-b...)
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Affinity Data
Ki: 5.29E+3nM
Assay Description:
Displacement of [3H]dofetolide from human ERG channel expressed in HEK293 cells by liquid scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50316936
(2-(1-methylpiperidin-3-yl)-1-(2-phenoxyethyl)-1H-b...)
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Affinity Data
Ki: 5.90E+3nM
Assay Description:
Displacement of [3H]dofetolide from human Erg
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50316936
(2-(1-methylpiperidin-3-yl)-1-(2-phenoxyethyl)-1H-b...)
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Affinity Data
IC50: >5.00E+3nM
Assay Description:
Inhibition of CYP3A4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI